Dr. Akram Sadeghi received her PhD in molecular genetics from Tarbiat Modares University of Iran in 2013, and curently works as Associate Prof. in the Microbial biotechnology Department of Agricultural Biotechnology Research Instituet of Iran (ABRII). Her activities are focused on production of biofertilizers and biopesticides and identification of abiotic stress tolerance mechanisms in Actinomycetes. In addition, she is familiar with different technologies, such as genetic engineering, metagenomics, molecular markers, bioinformatics and functional genomics.

1. Current Research

• Preparation and evaluation of three products based on growth promoting bacteria on greenhouse cucumber, tomato and bell pepper (mega project)
• Evaluation of growth promoting bacteria effects on damping off and crown and root rot of greenhouse cucumber, tomato and bell pepper

2. Performed Research

• Study on optimum growth conditions and designing formulation for increasing viability of native Streptomyces isolates as biocontrol agent
• Study of the mechanisms of salt tolerance in Streptomyces and their relation with biocontrol properties
• Effect of drought stress and using streptomyces bacterium on yield and yield components of maize hybrid KSC 260
• The effect of native PGPR Streptomyces isolates on wheat salt tolerance
• Isolation and molecular characterization of Streptomyces isolates effective on control of the fungal causal agent of sugar beet damping off and initial root rot

• Esmaeil Zade, N. S., Sadeghi, A., Moradi, P. 2019. Streptomyces strains alleviate water stress and increase peppermint (Mentha piperita) yield and essential oils. Plant and Soil. 434: 441–452.
• Sadeghi, A., Koobaz, P., Azimi, H., Karimi, E., Akbari, A. R. 2017. Plant growth promotion and suppression of Phytophthora drechsleri damping-off in cucumber by cellulase-producing Streptomyces. BioControl. 62: 805-819.
• Sheikhpour, M. Sadeghi, A., Yazdian, F., Mansoori, A., Movafagh, A. 2019. anticancer and apoptotic effects of ectoine and hydroxyectoine on non-small cell lung cancer cells: An in-vitro Investigation. Multidisciplinary Cancer Investigation. 3:14-19.
• Abbasi, S., Safaie, N., Sadeghi, A., Shamsbakhsh, M. 2019. Streptomyces strains induce resistance to Fusarium oxysporum f. sp. lycopersici race 3 in tomato through different molecular mechanisms. Frontiers in Microbiology. 10:1505.
• Sheikhpour, M. Sadeghi, A, Yazdian, F. 2014. Apoptotic effectsof ectoine and hydroxyectoine on human lung cancer cells. J Cancer Sci Ther. 6:10
• Sadeghi, A, Soltani, BM, Salehi Jouzani, G, Hadavand, H, Khayam Nekouei, M and Sadeghizadeh, M. 2014. Diversity of the ectoines biosynthesis genes in salt tolerant Streptomyces and evidence for inductive effect of ectoines on their accumulation. Microbiol Res,169: 699-708.
• Sadeghi, A, Soltani, BM, Salehi Jouzani, G, Karimi, E, Khayam Nekouei, M and Sadeghizadeh, M. 2014. Taxonomic study of a salt tolerant Streptomyces sp. strain C-2012 and the effect of salt and ectoine on lon expression level. Microbiol Res, 169: 232-238.
• Karimi, E., Sadeghi, A., Abaszadeh Dahaji, P., Dalvand, Y., Omidvari, M., Kakuei Nezhad, M. 2012. Biocontrol activity of salt tolerant Streptomyces isolates against phytopathogens causing root rot of sugar beet. Biocontrol Sci Technol 2012; 22: 333-349.
• Sadeghi, A., Karimi, E., Abaszadeh Dahaji, P., Ghorbani Javid, M., Dalvand, Y., Askari, H. 2012. Plant growth promoting activity of an auxin and siderophore producing isolate of Streptomyces under saline soil conditions. World J Microbiol Biotechnol 2012; 28: 1503-1509
• Sadeghi, A., Hesan, A. R., Askari, H., Naderi Qomi, D., Farsi, M., Majidi Hervan, E. (2009). Biocontrol of Rhizoctonia solani damping off of sugar beet with native Streptomyces strains under field conditions. Biocontrol Science and Technology, 19: 985-991.
• Sadeghi, A., Hessan, A. R., Askari, H., Aghighi, S., Shahidi. Bonjar, G. H. (2006). Biological Control Potential of Two Streptomyces isolates on of Rhizoctonia solani, The Causal Agent of Damping-off of Sugar Beet. Pakistan Journal of Biological Sciences 9(5): 904-910.
• Mardi, M., Ghaffari, M.R., Sadeghi, A., Salekdeh, S.G.H., Buerstmayr, H., Ghareyazie, B. (2006). Wheat genomics: molecular response of wheat to Fusarium head blight infection. Annual Wheat Newsletter 52: 69.
• Nazari, R., Akbarzadeh, A., Norouzian, D., Farahmand, B., Vaez, J., Sadeghi, A., Hormozi, F., Kiani-rad, M., Zarbakhsh, B. (2005). Applying intra-specific protoplast fusion in Streptomyces griseoflavus to increase the production of Desferrioxamine B. Current Science 88: 1815-1819

• Inventions (Patents):

• Sadeghi A. (2005) Biocontrol of fungal disease and growth promotion of plant using an abiotic stress resistant Streptomyces (Iranian Patent Grant Number:38505275)
• Sadeghi A., et al. (2008), Process of biocontrol of plant pathogens by a streptomyces strain resistant to environmental stresses (Iranian Patent Grant Number:38710077).
• Karimi E., Sadeghi A., Dalvand Y. (2012) Simple and low coast formulation to increase viability of Streptomyces bacteria (Iranian Patent Grant Number:390120785)

• Books

• Biosafety aspects of Genetically Modified Plants, Authors: Salehi Jouzani Gholamreza, Masoud Tohidfar and Akram Sadeghi, 2011, ABRII Press, 317 pages.  
• An introduction to Bioethics, Authors:  Hassan Rahnama, Masoud Tohidfar, Gholamreza Salehi Jouzani, Seyyed Mojtaba Khayam Nekouie, Akram Sadeghi, Saeed Soheilivand, 2008, ABRII Press, 270 pages.